Nope, I think you just get to learn tricks to smooth off edges and stuff, and also get to grips with the limits of what kinds of things you can and can't actually achieve at the given resolution. If you look on a couple off the dividing lines between panels on the body, they're actually really blocky and were causing me a few problems, but by significantly reducing the contrast between the highlights and lowlights, they sort of merged much more convincingly.

Also, the way the textures are rendered in game is slightly more sophisticated than how they are in the editor, somehow - I don't know how it works. So skins always look better in game or in the Save? [ Y / N ] screen than in the main editor.