When I first got my PS3 I had it folding like Superman on laundry day, but in the last year or so I've rarely fired up the client.

It's really just worry about shortening the lifespan of my (originally) 60Gb model, although, as I understand it, the motherboard problem is more about heat cycles than continual use.

It doesn't seem very environmentally conscious, either, leaving a power hungry phat PS3 on all night to crunch through a unit. When I'm downloading lots of content and I'll leave it on to fold at the same time, but aside from then my contributions have been a bit lacking.